A growth model of weight preferences, food consumption and public policy

Copyright @ 2013 Brunel University.In this paper we unify existing theories and empirical evidence on the origins of obesity and examine the e¤ects of scal policy on the dynamic evolution of weight. We build a dynamic general equilibrium growth model, with two sectors, one producing food and the other producing a composite consumption good. Weight is a function of rational choice as well as labor allocation between the two sectors. By estimating utility from weight and calibrating the US economy we show that (i) technological advances in agriculture decrease food prices and increase weight but not necessarily through higher food consumption but through lower calorie expenditure, (ii) reducing capital taxation, initially depresses weight levels through higher food prices; steady state food consumption decreases due to a price substitution e¤ect but weight soars due to lower calorie expenditure, (iii) reducing taxation on food increases food consumption and weight levels in equilibrium. Labor reallocation towards the less sedentary sector on one hand and higher income on the other function as contradictory forces

Kinetics of non-equilibrium quasiparticle tunneling in superconducting charge qubits

We directly observe low-temperature non-equilibrium quasiparticle tunneling in a pair of charge qubits based on the single Cooper-pair box. We measure even- and odd-state dwell time distributions as a function of temperature, and interpret these results using a kinetic theory. While the even-state lifetime is exponentially distributed, the odd-state distribution is more heavily weighted to short times, implying that odd-to-even tunnel events are not described by a homogenous Poisson process. The mean odd-state dwell time increases sharply at low temperature, which is consistent with quasiparticles tunneling out of the island before reaching thermal equilibrium.Comment: Replaced Figure 1 with color version, corrected more typos. Version submitted to PR

Software for the grouped optimal aggregation technique

The grouped optimal aggregation technique produces minimum variance, unbiased estimates of acreage and production for countries, zones (states), or any designated collection of acreage strata. It uses yield predictions, historical acreage information, and direct acreage estimate from satellite data. The acreage strata are grouped in such a way that the ratio model over historical acreage provides a smaller variance than if the model were applied to each individual stratum. An optimal weighting matrix based on historical acreages, provides the link between incomplete direct acreage estimates and the total, current acreage estimate

Characterization of a Differential Radio-Frequency Single-Electron Transistor

We have fabricated and characterized a new type of electrometer that couples two parallel single-electron transistors (SETs) to a radio-frequency tank circuit for use as a differential RF-SET. We demonstrate operation of this device in summing, differential, and single-SET operation modes, and use it to measure a Coulomb staircase from a differential single Cooper-pair box. In differential mode, the device is sensitive to uncorrelated input signals while screening out correlated ones.Comment: 3 pages, 3 figures, submitted to Applied Physics Letter

The H II Region/PDR Connection: Self-Consistent Calculations of Physical Conditions in Star-Forming Regions

We have performed a series of calculations designed to reproduce infrared diagnostics used to determine physical conditions in star forming regions. We self-consistently calculate the thermal and chemical structure of an H II region and photodissociation region (PDR) that are in pressure equilibrium. This differs from previous work, which used separate calculations for each gas phase. Our calculations span a wide range of stellar temperatures, gas densities, and ionization parameters. We describe improvements made to the spectral synthesis code Cloudy that made these calculations possible. These include the addition of a molecular network with ~1000 reactions involving 68 molecular species and improved treatment of the grain physics. Data from the Spitzer First Look Survey, along with other archives, are used to derive important physical characteristics of the H II region and PDR. These include stellar temperatures, electron densities, ionization parameters, UV radiation flux, and PDR density. Finally, we calculate the contribution of the H II region to PDR emission line diagnostics, which allows for a more accurate determination of physical conditions in the PDR.Comment: 60 pages, 35 figures, to be published in the Astrophysical Journal. Version with full resolution is available at http://www.pa.uky.edu/~nicholas/hii_pdr_high_res.pd

Detection of Leishmania infantum by PCR, serology and cellular immune response in a cohort study of Brazilian dogs

The sensitivity and specificity of PCR, serology (ELISA) and lymphoproliferative response to Leishmania antigen for the detection of Leishmania infantum infection were evaluated in a cohort of 126 dogs exposed to natural infection in Brazil. For PCR, Leishmania DNA from bone-marrow was amplified with both minicircle and ribosomal primers. The infection status and time of infection of each dog were estimated from longitudinal data. The sensitivity of PCR in parasite-positive samples was 98%. However, the overall sensitivity of PCR in post-infection samples, from dogs with confirmed infection, was only 68%. The sensitivity of PCR varied during the course of infection, being highest (78–88%) 0–135 days post-infection and declining to around 50% after 300 days. The sensitivity of PCR also varied between dogs, and was highest in sick dogs. The sensitivity of serology was similar in parasite-positive (84%), PCR-positive (86%) and post-infection (88%) samples. The sensitivity of serology varied during the course of infection, being lowest at the time of infection and high (93–100%) thereafter. Problems in determining the specificity of serology are discussed. The sensitivity and specificity of cellular responsiveness were low. These data suggest that PCR is most useful in detecting active or symptomatic infection, and that serology can be a more sensitive technique for the detection of all infected dogs

Viral delivery of antioxidant genes as a therapeutic strategy in experimental models of amyotrophic lateral sclerosis.

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder with no effective treatment to date. Despite its multi-factorial aetiology, oxidative stress is hypothesized to be one of the key pathogenic mechanisms. It is thus proposed that manipulation of the expression of antioxidant genes that are downregulated in the presence of mutant SOD1 may serve as a therapeutic strategy for motor neuronal protection. Lentiviral vectors expressing either PRDX3 or NRF2 genes were tested in the motor neuronal-like NSC34 cell line, and in the ALS tissue culture model, NSC34 cells expressing the human SOD1(G93A) mutation. The NSC34 SOD1(G93A) cells overexpressing either PRDX3 or NRF2 showed a significant decrease in endogenous oxidation stress levels by 40 and 50% respectively compared with controls, whereas cell survival was increased by 30% in both cases. The neuroprotective potential of those two genes was further investigated in vivo in the SOD1(G93A) ALS mouse model, by administering intramuscular injections of adenoassociated virus serotype 6 (AAV6) expressing either of the target genes at a presymptomatic stage. Despite the absence of a significant effect in survival, disease onset or progression, which can be explained by the inefficient viral delivery, the promising in vitro data suggest that a more widespread CNS delivery is needed

Glass Ceiling Commission - The Impact of the Glass Ceiling and Structural Change on Minorities and Women

Glass Ceiling ReportGlassCeilingBackground12StructuralChange.pdf: 9391 downloads, before Oct. 1, 2020

Effectiveness of an inlet flow turbulence control device to simulate flight noise fan in an anechoic chamber

A hemispherical inlet flow control device was tested on a 50.8 cm. (20-inch) diameter fan stage in the NASA-Lewis anechoic chamber. The control device used honeycomb and wire mesh to reduce turbulence intensities entering the fan. Far field acoustic power level results show about a 5 db reduction in blade passing tone and about 10 dB reduction in multiple pure tone sound power at 90% design fan speed with the inlet device in place. Hot film cross probes were inserted in the inlet to obtain data for two components of the turbulence at 65 and 90% design fan speed. Without the flow control device, the axial intensities were below 1.0%, while the circumferential intensities were almost twice this value. The inflow control device significantly reduced the circumferential turbulence intensities and also reduced the axial length scale

Behavior of the Dripping Faucet over a Wide Range of the Flow Rate

The time interval of successive water-drips from a faucet was examined over a wide range of the flow rate. The dripping interval alternately exhibits a stable state and a chaotic state as the flow rate increases. In the stable state, the volume of the drip is kept constant at fixed flow rates, and the constant volume increases with the flow rate. In the chaotic state, in addition to a mechanics that the drip is torn by its own weight, the vibration of the drip on the faucet takes part in the strange behavior of the interval.Comment: 7 pages, 7 figures, to be published in J. Phys. Soc. Jpn vol 68-2(1999